stillingsbetegnelse: Postdoc in Immunology

jobbeskrivelse:
The scientific focus of the laboratory lies on the recognition of viruses at mucosal surfaces. With this announced position we intend to strengthen our systems immunology efforts with the goal of using novel approaches to unravel the transcriptional regulation of dendritic cells, the main pathogen recognizing cells in the body. We benefit from synergistic effects within the section of virology, but are immunologists by training and have strong bonds to the immunology section. There are multiple young groups at the institute working closely together to create the motivating environment needed for good basic science. The laboratory is part of the section for virology, one of the five Sections comprising the Department employing 220 persons. The section for virology strives to increase the current knowledge of new and existing viral pathogens, to bridge both animal and human health and life science and engineering. We collaborate with leading partners, both nationally and internationally, in order to contribute new scientific discoveries, develop innovative tools and services and novel types of interventions. We conduct virus infection experiments from the molecular level to the disease level within a range of appropriate ‘state of the art’ containment facilities. Responsibilities and tasks We are seeking a postdoctoral fellow to join our studies on the transcriptional regulation of mucosal dendritic cell subsets. Dendritic cells are professional antigen presenting cells crucial for directing immune homeostasis and inflammation. Different subsets of dendritic cells orchestrate different types of immunity, which has a strong impact on pathogenicity and clearance of viruses. The goal of our studies is to better understand dendritic cell subset development and function by unravelling the transcriptional landscape underlying subset differentiation in murine and human mucosal tissues. This will entail sorting of dendritic cells directly from human and mouse mucosal tissues and perform ATAC-Seq on these cells, which will be followed by extended computational analysis. The content of the position will be Research only. Some teaching opportunities, such as guidance of students within the lab, may arise. It may also involve handling other assignments to a very limited extent. Qualifications Candidates should have a PhD degree or equivalent. The candidate should have a background in immunology or bioinformatics, and should have at least basic experience in programming and/or systems biology in general. The project is built on basic immunology questions, and knowledge of cellular immunology methods will be helpful. In this regard, we are looking in particular for candidates with experience in harvesting primary cells from mouse and human mucosal tissues, multi-fluorescent flow cytometry, or ChIP-Seq. We offer We offer an interesting and challenging job in an international environment focusing on education, research, public-sector consultancy and innovation, which contribute to enhancing the economy and improving social welfare. We strive for academic excellence, collegial respect and freedom tempered by responsibility. The Technical University of Denmark (DTU) is a leading technical university in northern Europe and benchmarks with the best universities in the world. Salary and terms of employment The appointment will be based on the collective agreement with the Confederation of Professional Associations. The allowance will be agreed with the relevant union. The laboratory is located in Frederiksberg on the DTU Vet Campus. In 2017 DTU Vet is moving to Lyngby campus just north of Copenhagen. The period of employment is 2 years (with the possibility of an extension, funding permitted). Further information Further information may be obtained from Head of Section Thomas Kledal, +45 2012 1656 or from Associate Professor Katharina Lahl, email klah (at) vet.dtu.dk You can read more about DTU Vet at http://www.vet.DTU.dk Application procedure: Plea

Arbejdsgiver Navn: Danmarks Tekniske Universitet

Arbejdsgiver telefonnummer: 45252525

Arbejdsgiver faxnummer: 45881799

Job kort beskrivelse:
Undervisning og forskning på universiteter og højere læreranstalter

land: Danmark

region: Hovedstaden

krævede uddannelse: Ikke angivet

Kilde til jobtilbud: AMS, Offentlige arbejdsformidlinger, Danmark